Probably the vinegar can be reused many times, don't know if some active part of it gets exhausted from it? I use CLR for all those calcium deposits on plumbing, also water kettles etc, but women use vinegar....
I reuse CLR, only sometimes throw out the dirty bottom. Didn't notice it not doing the job even after many reuse.
Trick is always to find the most efficient container for the job, so you don't need too much of the stuff, vinegar or CLR. Always handy to have on hand those clear plastic bins of various sizes. For vinegar I'd put the lid on the bin to keep the smell in, don't know if vinegar evaporates or the active ingredient in it.